Topic 12: Respiration

Cambridge IGCSE 0610 / 0970 · 7 min read

Respiration is one of the most important processes in living things — it is how every cell releases the energy stored in food. Without it, muscles could not move, nerves could not work, and life would stop. In this topic you will learn the difference between aerobic and anaerobic respiration, write their equations, and see why oxygen makes such a big difference to how much energy is released.

What respiration is and why it matters

Respiration is the chemical reactions in cells that break down nutrient molecules to release energy. It happens in all living cells, all the time. The energy released is used for many processes.

Do not confuse respiration with breathing: breathing moves air in and out of the lungs, while respiration is the release of energy inside cells.

Aerobic respiration

Aerobic respiration is the release of a relatively large amount of energy by the breakdown of glucose using oxygen. It is the main way cells release energy.

Because it gives so much energy, aerobic respiration is used whenever enough oxygen is available.

Anaerobic respiration

Anaerobic respiration is the release of a relatively small amount of energy by the breakdown of glucose without using oxygen. It is useful when oxygen is in short supply, but it releases far less energy.

The reactions of anaerobic respiration in yeast are also called fermentation.

Oxygen debt and recovery

During vigorous exercise, muscles may respire anaerobically because oxygen cannot be delivered fast enough. This produces lactic acid, which builds up and can cause muscle fatigue and cramp.

This is why your breathing and heartbeat stay fast even after you stop running — the body is repaying the oxygen debt.

Key terms

Respiration
The chemical reactions in cells that break down nutrient molecules to release energy.
Aerobic respiration
The release of a relatively large amount of energy by the breakdown of glucose using oxygen.
Anaerobic respiration
The release of a relatively small amount of energy by the breakdown of glucose without using oxygen.
Glucose
The sugar broken down in respiration to release energy.
Lactic acid
The product of anaerobic respiration in muscles, which can cause fatigue.
Fermentation
Anaerobic respiration in yeast, producing ethanol and carbon dioxide.
Oxygen debt
The extra oxygen needed after exercise to break down the lactic acid that built up.
Active transport
The movement of substances across a membrane using energy from respiration.
Breathing
The movement of air into and out of the lungs, different from respiration.
Ethanol
The alcohol produced by anaerobic respiration in yeast.

Exam technique

Quick check
What is produced when muscles respire anaerobically?
  1. Ethanol and carbon dioxide
  2. Lactic acid
  3. Oxygen and glucose
  4. Water only
Show answer
Answer: B. In muscles, anaerobic respiration breaks glucose down into lactic acid, releasing a small amount of energy without oxygen.

Test yourself

Practise exam-style questions on this topic.

Go to the quiz →
All study notes